Testosterone Treatment and Fractures in Men with Hypogonadism To the Editor

To the Editor: One in five men older than 50 years of age will have an osteoporosis-related fracture, which is often associated with high risks of complications and death and high costs.(1) Guidelines from the Endocrine Society suggest that men with hypogonadism should have their bone mineral density measured,(2) given that hypogonadism causes a decrease in bone mineral density,(3) whereas testosterone-replacement therapy increases bone mineral density when used in concert with calcium and vitamin D supplementation.(4) A recent study showed that only approximately 7% of men who begin receiving testosterone-replacement therapy have their bone mineral density assessed.(5) This situation is . . .