Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation

被引：2
|
作者：
Ye, Xianwen [1 ,2 ]
Huang, Zixuan [1 ,2 ]
Li, Yi [1 ,2 ]
Wang, Mengjiao [1 ,2 ]
Meng, Wanyu [1 ,2 ]
Miao, Maojian [1 ,2 ]
Cheng, Jingdong [1 ,2 ]
机构：
[1] Fudan Univ, Minhang Hosp, Shanghai, Peoples R China
[2] Fudan Univ, Inst Biomed Sci, Shanghai Key Lab Med Epigenet, Int Colab Med Epigenet & Metab, Shanghai, Peoples R China
来源：
CELL RESEARCH | 2024年 / 34卷 / 07期
基金：
中国国家自然科学基金; 国家重点研发计划;
关键词：
TRANSFORMATION;
D O I：
10.1038/s41422-024-00962-z
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：522 / 525
页数：4
相关论文
共 50 条
  • [31] The role of Pdcd4 in tumour suppression and protein translation
    Wang, Qing
    Yang, Hsin-Sheng
    BIOLOGY OF THE CELL, 2018, 110 (08) : 169 - 177
  • [32] Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation
    Singh, P.
    Wedeken, L.
    Waters, L. C.
    Carr, M. D.
    Klempnauer, K-H
    ONCOGENE, 2011, 30 (49) : 4864 - 4873
  • [33] mTOR-dependent transcriptional repression of Pdcd4 tumor suppressor in lung cancer cells
    Vikhreva, P. N.
    Shepelev, M. V.
    Korobko, I. V.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2014, 1839 (01): : 43 - 49
  • [34] Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation
    P Singh
    L Wedeken
    L C Waters
    M D Carr
    K-H Klempnauer
    Oncogene, 2011, 30 : 4864 - 4873
  • [35] Mitogen- and phosphorylation site-specific degradation mechanisms of tumor suppressor PDCD4 in human HCC cells
    Ozaki, Iwata
    Hamajima, Hiroshi
    Xia, Jinghe
    Qi, Jingyan
    Mizuta, Toshihiko
    Anzai, Keizo
    Matsuhashi, Sachiko
    HEPATOLOGY, 2013, 58 : 464A - 464A
  • [36] Structural basis for translational inhibition by the tumour suppressor Pdcd4
    Loh, Portia G.
    Yang, Hsin-Sheng
    Walsh, Martin A.
    Wang, Qing
    Wang, Xiaoxing
    Cheng, Zhihong
    Liu, Dingxiang
    Song, Haiwei
    EMBO JOURNAL, 2009, 28 (03): : 274 - 285
  • [37] Have Tumor Suppressor PDCD4 and its Counteragent Oncogenic miR-21 Gone Rogue?
    Young, Matthew R.
    Santhanam, Arti N.
    Yoshikawa, Noriko
    Colburn, Nancy H.
    MOLECULAR INTERVENTIONS, 2010, 10 (02) : 76 - 79
  • [38] Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit
    Querido, Jailson Brito
    Sokabe, Masaaki
    Diaz-Lopez, Irene
    Gordiyenko, Yuliya
    Zuber, Philipp
    Du, Yifei
    Albacete-Albacete, Lucas
    Ramakrishnan, V.
    Fraser, Christopher S.
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [39] PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance
    Zennami, Kenji
    Choi, Su Mi
    Liao, Ross
    Li, Ying
    Dinalankara, Wikum
    Marchionni, Luigi
    Rafiqi, Fatema H.
    Kurozumi, Akira
    Hatano, Koji
    Lupold, Shawn E.
    MOLECULAR CANCER RESEARCH, 2019, 17 (02) : 618 - 627
  • [40] Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4
    Grkovic, Tanja
    Blees, Johanna S.
    Bayer, Magdalena M.
    Colburn, Nancy H.
    Thomas, Cheryl L.
    Henrich, Curtis J.
    Peach, Megan L.
    McMahon, James B.
    Schmid, Tobias
    Gustafson, Kirk R.
    MARINE DRUGS, 2014, 12 (08): : 4593 - 4601
12345