cDNA macroarray for analysis of gene expression profiles in prostate cancer

被引：0
|
作者：
ZHONG Weide HE Huichan BI Xuecheng OU Rubiao JIANG Shaoai and LIU LiangshiDepartment of Urology Guangzhou First Municipal Peoples Hospital Guangzhou Medical College Guangzhou China Zhong WD He HC Bi XC Ou RB and Jiang SA College of Life Science Sun Yatsen University Guangzhou China Liu LS [510180 ,510180 ]
机构：
来源：
ChineseMedicalJournal | 2006年 / 07期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background Early diagnosis and timely treatment are important for improving therapeutic efficiency of prostate cancer. DNA array is a new bio-technology for disease diagnosis. This study was conducted to diagnose prostate cancer with cDNA macroarray and analysis gene expression profiles of some selective genes in prostate cancer. Methods Total RNA was isolated from patients with prostate cancer and from normal people, and poly(A) RNA was further purified. Then it was analyzed for differentially expressed genes in prostate cancer and normal prostate by cDNA macroarray system. Results There were different expressions in the nine prostate-associated specific genes in prostate cancer as compared with normal prostate, in which, 7 were significantly upregulated and 2 were down-regulated. Conclusion As a diagnostic approach at molecular level, the cDNA macroarray is an effectively diagnostic method for prostate cancer.
引用
收藏
页码：570 / 573
页数：4
相关论文
共 50 条
  • [31] Analysis for methyl jasmonate-specific expression changes in Arabidopsis by cDNA macroarray
    Sasaki-Sekimoto, Y
    Taki, N
    Obayashi, T
    Ainai, T
    Kobayashi, Y
    Asamizu, E
    Nakamura, Y
    Kuromori, T
    Hirayama, T
    Shinozaki, K
    Masuda, T
    Shimada, H
    Takamiya, K
    Shibata, D
    Tabata, S
    Ohta, H
    [J]. PLANT AND CELL PHYSIOLOGY, 2003, 44 : S112 - S112
  • [32] Development of a prostate cDNA microarray and statistical gene expression analysis package
    Carlisle, AJ
    Prabhu, VV
    Elkahloun, A
    Hudson, J
    Trent, JM
    Linehan, WM
    Williams, ED
    Emmert-Buck, MR
    Liotta, LA
    Munson, PJ
    Krizman, DB
    [J]. MOLECULAR CARCINOGENESIS, 2000, 28 (01) : 12 - 22
  • [33] Study of expression profiles in the striatum and the hippocampus of normal and neurodevelopmentally compromised rats using cDNA macroarray methodology
    Gak, E
    Koronyo-Hamaoui, M
    Zuckerman, L
    Guetta, E
    Barkai, G
    Goldman
    Weiner, I
    [J]. AMERICAN JOURNAL OF MEDICAL GENETICS, 2002, 114 (07): : 883 - 883
  • [34] cDNA macroarray analysis of gene expression changes in rat brain after a single administration of a 2-aminoadamantane derivative
    Vakhitova, YV
    Yamidanov, RS
    Vakhitov, VA
    Seredenin, SB
    [J]. MOLECULAR BIOLOGY, 2005, 39 (02) : 244 - 252
  • [35] cDNA macroarray analysis of gene expression changes in rat brain after a single administration of a 2-aminoadamantane derivative
    Yu. V. Vakhitova
    R. S. Yamidanov
    V. A. Vakhitov
    S. B. Seredenin
    [J]. Molecular Biology, 2005, 39 : 244 - 252
  • [36] Analysis of gene expression profiles of PC3 prostate cancer cells treated with genistein
    Li, YW
    Sarkar, FH
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2002, 11 (10) : 1232S - 1232S
  • [37] CDNA array analysis of gene expression profiles in brain of mice exposed to manganese
    Baek, SY
    Cho, JH
    Kim, ES
    Kim, HJ
    Yoon, S
    Kim, BS
    Kim, JB
    Lee, CR
    Yoo, C
    Lee, JH
    Lee, H
    Park, J
    Kim, JW
    Kim, Y
    [J]. INDUSTRIAL HEALTH, 2004, 42 (03) : 315 - 320
  • [38] Regular aspirin use and gene expression profiles in prostate cancer patients
    Stopsack, Konrad H.
    Ebot, Ericka M.
    Downer, Mary K.
    Gerke, Travis A.
    Rider, Jennifer R.
    Kantoff, Philip W.
    Mucci, Lorelei A.
    [J]. CANCER CAUSES & CONTROL, 2018, 29 (08) : 775 - 784
  • [39] Regular aspirin use and gene expression profiles in prostate cancer patients
    Konrad H. Stopsack
    Ericka M. Ebot
    Mary K. Downer
    Travis A. Gerke
    Jennifer R. Rider
    Philip W. Kantoff
    Lorelei A. Mucci
    [J]. Cancer Causes & Control, 2018, 29 : 775 - 784
  • [40] Characteristic gene expression profiles of benign prostatic hypertrophy and prostate cancer
    Endo, Takumi
    Uzawa, Katsuhiro
    Suzuki, Hiroyoshi
    Tanzawa, Hideki
    Ichikawa, Tomohiko
    [J]. INTERNATIONAL JOURNAL OF ONCOLOGY, 2009, 35 (03) : 499 - 509
12345