Mechanism and design of allosteric activators of SIRT1

被引：0
|
作者：
Fei Liu [1 ]
Ningning Pang [1 ]
RuiMing Xu [2 ]
Na Yang [1 ]
机构：
[1] State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai University
[2] National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of
来源：
Protein & Cell | 2023年 / 14卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
<正>Dear Editor,The sirtuin family Nicotinamide adenine dinucleotide-dependent deacetylases have important roles in many biological processes (Milne and Denu, 2008). SIRT1 is a mammalian homolog of yeast Sir2, which is the founding member of the sirtuin family. Many SIRT1 substrates have been reported, including histones, p53, FOXOs, and PGC1α (Hsu et al., 2013).
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页码：387 / 392
页数：6
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