Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus

被引：0
|
作者：
Kakorin, S., V [1 ,2 ,3 ]
Kruglyy, L. B. [4 ]
Mkrtumyan, A. M. [5 ]
机构：
[1] City Clin Hosp 4, Med Sci, Moscow, Russia
[2] City Clin Hosp 4, Moscow, Russia
[3] City Clin Hosp 4, Dept Emergency Cardiol, Moscow, Russia
[4] First Moscow State Med Univ, Dept Hosp Therapy 2, Moscow, Russia
[5] Moscow State Med & Den Univ, Moscow, Russia
来源：
DIABETES MELLITUS | 2013年 / 16卷 / 02期
关键词：
type 2 diabetes mellitus; acute coronary syndrome; myocardial infarction; metabolic ischemia; macroangiopathy; microangiopathy; revascularization;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corresponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chronic ischemic alterations in myocardium (the so-called " metabolic ischemia"), as well as concomitant microangiopathy. It is more common for patients with T2DM to develop such complications of ACS as cardiogenic shock, acute left ventricular failure and arrhythmia that result in increased lethality during early hours of hospital admission when myocardial necrosis is yet to occur. Percutaneous translumenal intervention is by far the most effective method of ACS management in patients with T2DM. Whenever it is not available, a thrombolytic approach is indicated.
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页码：36 / 42
页数：7
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