PLASMA FIBRINOGEN LEVEL IN DIABETICS WITH COMPLICATIONS - A PROSPECTIVE STUDY

Background: The objective of this study was to determine the role of fibrinogen concentration in the development of complications in Pakistani diabetics. Material & Methods: A total of 120 subjects ranging in age between 40 and 70 years from the staff members of Saidu Medical College, Swat and diabetics from the Medical OPD of Saidu Group of Teaching Hospitals were selected. Parameters like fibrinogen concentration, body weight, height, body mass index, and serum glucose concentration were measured and compared among all the groups according to the inclusion and exclusion criteria. Results: Data indicated a highly significant increase in the parameters like body weight, fibrinogen concentration and plasma viscosity in diabetics with complications than diabetics with out complications and healthy control subjects. Conclusion: Fibrinogen concentration and plasma viscosity is significantly elevated in diabetics with complications.