An atypical paroxysmal positioning nystagmus (PPNy), ''reversed'' in its directional components, is a rare finding in patients suffering from benign paroxysmal positioning vertigo (BPPV). It poses problems of pathophysiogenetic interpretation, differential diagnosis with a CNS lesion and therapeutic strategy. Such a finding was observed in 7 patients (out of a total of 450 BPPV) and took on the typical PPNy pattern after repeated diagnostic manoeuvres. These aspects are incompatible with the ''heavy cupula'' mechanism (cupulolithiasis) and are better explained by the presence of ''free endolymph aggregates'' (canalolithiasis) within the posterior semicircular canal (p.s.c). Moreover, canalolithiasis would also permit a more convincing interpretation of all the clinical findings observed in typical p.s.c.-BPPV.
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G dAnnunzio Univ Chieti Pescara, Dept Oral & Nanobiotechnol Sci, ENT Inst, I-74100 Taranto, ItalyG dAnnunzio Univ Chieti Pescara, Dept Oral & Nanobiotechnol Sci, ENT Inst, I-74100 Taranto, Italy
De Stefano, Alessandro
Dispenza, Francesco
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San Giovanni di Dio Hosp Agrigento, Dept Otolaryngol, Agrigento, ItalyG dAnnunzio Univ Chieti Pescara, Dept Oral & Nanobiotechnol Sci, ENT Inst, I-74100 Taranto, Italy
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Western Univ, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr, London, ON, CanadaWestern Univ, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr, London, ON, Canada
You, Peng
Instrum, Ryan
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Western Univ, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr, London, ON, CanadaWestern Univ, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr, London, ON, Canada
Instrum, Ryan
Parnes, Lorne
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Western Univ, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr, London, ON, CanadaWestern Univ, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr, London, ON, Canada