Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)

被引：0
|
作者：
Shapovalyants, O. S. [1 ]
Nikonova, T. V. [1 ]
机构：
[1] Endocrinol Res Ctr, Moscow, Russia
来源：
DIABETES MELLITUS | 2011年 / 14卷 / 02期
关键词：
type 1 mellitus diabetes; autoantibodies; immunnity; zinc transporter 8;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The progressive loss of beta cells in Type 1 Diabetes (T1D) is a result of chronic autoimmune attack targeted at diverse molecules expressing in the pancreatic beta cells. The appearance of cellular and humoral autoimmunity precedes the clinical manifestation of T1D. There are several autoantigens which are supposed to be involved in pathogenesis of TD1. Zinc transporter 8 (ZnT8; Slc30A8) was identified as a novel T1D autoimmunity target.
引用
收藏
页码：18 / 22
页数：5
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