DEVELOPMENT OF A 3D GRADIENT-BASED METHOD FOR VOLUME QUANTITATION IN SPECT

被引：4

作者：

LONG, DT ^{[1
]}

KING, MA ^{[1
]}

GENNERT, MA ^{[1
]}

机构：

[1] WORCESTER POLYTECH INST,DEPT COMP SCI,WORCESTER,MA 01609

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 1991年 / 38卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1109/23.289384

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A three-dimensional (3D) method for quantifying organ and lesion volume in SPECT is described. A 3D edge detection technique based on a 3D gradient operator is used to define the boundary of a radionuclide distribution in typical low contrast, high noise SPECT images. The method combines pre- and post-reconstruction filtering of the SPECT images with a 3D adaptation of interpolative background subtraction to provide adequate noise reduction for reliable boundary definition. Simulation studies have shown the method to provide a direct measurement of relatively small volumes in SPECT images with good reproducibility and minimal operator bias. The method is applicable to quantifying volume of both "hot" and "cold" lesions.

引用

页码：748 / 754

页数：7

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