DISTRIBUTION OF PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE-PEROXIDASE (PHGPX) IN RAT TESTIS MITOCHONDRIA

被引：47
|
作者：
GODEAS, C [1 ]
SANDRI, G [1 ]
PANFILI, E [1 ]
机构：
[1] UNIV TRIESTE,DEPT BIOCHEM BIOPHYS & MACROMOLEC CHEM,I-34127 TRIESTE,ITALY
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1994年 / 1191卷 / 01期
关键词：
MITOCHONDRION; PHOSPHOLIPID HYDROPEROXIDE; GLUTATHIONE PEROXIDASE; SELENIUM; GLUTATHIONE; (RAT TESTIS);
D O I：
10.1016/0005-2736(94)90242-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in isolated rat testis mitochondria was investigated, using a reverse sucrose density gradient centrifugation procedure for the separation of the inner and outer membranes and the contact sites between the two membranes. The results indicate that PHGPx is largely localized in the contact sites fraction. This finding might therefore suggest that the enzyme has more than just an antioxidant function.
引用
收藏
页码：147 / 150
页数：4
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