HEPATITIS VIRUS-RELATED HEPATOCARCINOGENESIS

被引：32
|
作者：
HINO, O
KAJINO, K
机构：
来源：
INTERVIROLOGY | 1994年 / 37卷 / 02期
关键词：
HEPATITIS B VIRUS; HEPATITIS C VIRUS; CHRONIC HEPATITIS; HEPATOCARCINOGENESIS; RECOMBINOGENIC PROTEIN; GENOMIC INSTABILITY;
D O I：
10.1159/000150368
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We propose that hepatitis virus can cause an increase in the incidence of liver cancer by a combination of two mechanisms: (1) cell killing and stimulation of mitosis leading to an accumulation of events necessary for transformation, and (2) an increase in chromosomal instability mediated by induced recombinogenic proteins(s) during chronic hepatitis.
引用
收藏
页码：133 / 135
页数：3
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