EFFECTIVE INTRARTERIAL INFUSION CHEMOTHERAPY FOR LOCALLY RECURRENT BREAST-CANCER WITH AXILLARY METASTATIC BRACHIAL PLEXOPATHIA - A CASE-REPORT

Locally recurrent breast cancer with involvement of the brachial plexus still represents a challenging therapeutic problem. The favourable results obtained in patients with primary advanced and locally recurrent breast cancer with high-dose loco-regional chemotherapy via implantable systems induced us to employ this treatment in a 50-year old patient with locoregionally recurrent breast tumor infiltrating the brachial plexus. Four cycles of mitoxantrone (14 mg/m2) infused through the sublavian artery caused a complete clinical remission with no local or systemic side effects. Intraarterial infusion chemotherapy seems to be a promising modality for the treatment of locoregionally advanced recurrent breast cancer.