HUMAN DIADENOSINE 5',5'''-P-1,P-4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE IS A MEMBER OF THE MUTT FAMILY OF NUCLEOTIDE PYROPHOSPHATASES

被引:60
|
作者
MATHEW, N [1 ]
THORNE, H [1 ]
HANKIN, S [1 ]
WILKINSON, MC [1 ]
NUNEZ, C [1 ]
BARRACLOUGH, R [1 ]
MCLENNAN, AG [1 ]
机构
[1] UNIV LIVERPOOL,DEPT BIOCHEM,LIVERPOOL L69 3BX,MERSEYSIDE,ENGLAND
关键词
D O I
10.1042/bj3110717
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The cDNA and derived amino acid sequence of human diadenosine 5', 5'''-P-1, P-4-tetraphosphate pyrophosphohydrolase have been determined with the aid of the GenBank Expressed Sequence Tag database. This enzyme possesses a modification of the MuT sequence motif found in certain nucleotide pyrophosphatases. It is unrelated to the enzymes of diadenosine tetraphosphate catabolism found in prokaryotes and fungi.
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页码:717 / 721
页数:5
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