QUANTITATIVE CHARACTERIZATION OF ANTIGENS USING MONOCLONAL-ANTIBODY REACTIVITIES

被引：0
|
作者：
DOPAZO, J
TABERNER, A
MOYA, A
机构：
[1] CSIC,CTR INVEST BIOL,UEI FITOPATOL,E-28006 MADRID,SPAIN
[2] UNIV VALENCIA,DEPT GENET,E-46100 VALENCIA,SPAIN
来源：
COMPUTER APPLICATIONS IN THE BIOSCIENCES | 1993年 / 9卷 / 01期
关键词：
D O I：
暂无
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
A multipurpose program that empirically relates antigenic reactivities with monoclonal antibodies (MAbs) to genetic distances is presented. The program uses a set of known genetic pairwise distances to weigh each MAb depending on its capacity to define groups of taxonomically related antigens. This allows highly accurate identification and classification of unknown antigens. Also, the weights obtained constitute a quantitative measure of epitope conservation and can be used for improved vaccine design.
引用
收藏
页码：101 / 107
页数：7
相关论文
共 50 条
  • [41] REACTIVITIES OF A MONOCLONAL-ANTIBODY DIRECTED AGAINST AN IMMUNOSUPPRESSIVE MOLECULE IN BOAR SEMINAL PLASMA
    VESELSKY, L
    LANDA, V
    DOSTAL, J
    BEHALOVA, E
    STANEK, R
    VINTER, P
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1993, 24 (03) : 187 - 200
  • [42] DETECTION OF PLATELET AUTOANTIBODIES USING THE MONOCLONAL-ANTIBODY IMMOBILIZATION OF PLATELET ANTIGENS (MAIPA) ASSAY
    JOINER, K
    NANCE, S
    KEASHENSCHNELL, MA
    MURPHY, S
    TRANSFUSION, 1995, 35 (10) : S68 - S68
  • [43] DETECTION OF SERUM ANTIGENS USING MOUSE MONOCLONAL-ANTIBODY 47D10
    HO, MK
    DOMBKOWSKI, D
    CARNEY, WP
    RABIN, H
    SULLIVAN, M
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1987, 28 : 358 - 358
  • [44] ELECTRON-MICROSCOPIC LOCALIZATION OF BABOON ACROSOMAL ANTIGENS USING ANTISPERM MONOCLONAL-ANTIBODY
    GICHUHI, PM
    ISAHAKIA, MA
    ACTA ANATOMICA, 1992, 144 (02): : 178 - 183
  • [45] ANALYSIS OF CELL-SURFACE ANTIGENS IN INTERDIGITATING CELLS OF MICE USING MONOCLONAL-ANTIBODY
    TANAKA, S
    UDA, H
    MARUYAMA, T
    ZOOLOGICAL SCIENCE, 1987, 4 (06) : 996 - 996
  • [46] MONOCLONAL-ANTIBODY CHARACTERIZATION OF SURFACE-ANTIGENS IN CHILDHOOD T-CELL LYMPHOID MALIGNANCIES
    ROPER, M
    CRIST, WM
    METZGAR, R
    RAGAB, AH
    SMITH, S
    STARLING, K
    PULLEN, J
    LEVENTHAL, B
    BARTOLUCCI, AA
    COOPER, MD
    BLOOD, 1983, 61 (05) : 830 - 837
  • [47] MONOCLONAL-ANTIBODY REACTIVE WITH HUMAN-COLON CARCINOMA ANTIGENS
    CHAN, JC
    SCANLON, M
    ORDONEZ, N
    CHI, K
    HYBRIDOMA, 1985, 4 (01): : 76 - 76
  • [48] MONOCLONAL-ANTIBODY PROBES FOR OPTIC-NERVE AND RETINAL ANTIGENS
    STERNBERGER, NH
    DELCERRO, M
    STERNBERGER, LA
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1986, 45 (03): : 346 - 346
  • [49] IMMUNOPEROXIDASE LOCALIZATION OF MONOCLONAL-ANTIBODY DEFINED ANTIGENS IN FIXED TISSUE
    ATKINSON, BF
    ERNST, CS
    STEPLEWSKI, Z
    KOPROWSKI, H
    HYBRIDOMA, 1982, 1 (03): : 342 - 342
  • [50] CHARACTERIZATION OF HUMAN MONOCLONAL-ANTIBODY CLONES USING DNA HYBRIDIZATION TECHNOLOGY
    BERMANWONG, E
    BOWEN, T
    DIMNIK, L
    DAWSON, D
    HOAR, D
    CLINICAL RESEARCH, 1985, 33 (02): : A372 - A372
12345