Hip structure analysis by DXA of teriparatide treatment: A 24-month follow-up clinical study

被引：4
|
作者：
Mochizuki, Takeshi [1 ]
Yano, Koichiro [2 ]
Ikari, Katsunori [2 ]
Kawakami, Kosei [1 ]
Hiroshima, Ryo [1 ]
Koenuma, Naoko [1 ]
Ishibashi, Mina [1 ]
Shirahata, Toshikatsu [3 ]
机构：
[1] Kamagaya Gen Hosp, Dept Rheumatol & Orthopaed Surg, Chiba, Japan
[2] Tokyo Womens Med Univ, Inst Rheumatol, Tokyo, Japan
[3] Chibanishi Gen Hosp, Dept Orthopaed Surg, Chiba, Japan
来源：
JOURNAL OF ORTHOPAEDICS | 2016年 / 13卷 / 04期
关键词：
Dual-energy X-ray absorptiometry; Hip structure analysis; Osteoporosis; Rheumatoid arthritis; Teriparatide;
D O I：
10.1016/j.jor.2016.09.001
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Objective: The objective of this study was to perform a hip structure analysis (HSA) of teriparatide (TPTD) treatment in women with postmenopausal osteoporosis. Methods: The study included 96 patients with postmenopausal osteoporosis and received 20 mu g TPTD daily. HSA was performed by dual-energy X-ray absorptiometry. Results: The percent changes from baseline for the cross-sectional moment of inertia, section modulus, buckling ratio, and femoral strength index based on HSA results were 9.8% (p < 0.01), 10.7%, 3.3%, and 14.9% (p < 0.01), respectively, at 24 months. Conclusion: Based on the HSA results obtained with DXA, TPTD was effective for hip structures. (C) 2016 Prof. PK Surendran Memorial Education Foundation. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.
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页码：414 / 418
页数：5
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