SMALL CELL LUNG CANCER;
CHEMOTHERAPY;
PACLITAXEL;
DOCETAXEL;
CPT-11;
TOPOTECAN;
GEMCITABINE;
D O I:
10.1016/S0169-5002(10)80018-2
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Recently there has been a number of new active drugs which have been identified for treating patients with SCLC. These drugs include paclitaxel, docetaxel, CPT-11, topotecan and gemcitabine. The range of response rates are as follows for each of the drugs given: (I) to previously untreated patients: paclitaxel (34-41%), topotecan (39%) and gemcitabine (30%), and (2) to previously treated patients: docetaxel (28%), CPT-11 (47%) and topotecan (35%). Further studies with these new drugs utilized in combination chemotherapeutic regimens are needed to define the role of these agents in the treatment of patients with SCLC.