NEW DRUGS FOR TREATING SMALL-CELL LUNG-CANCER

被引:11
|
作者
ETTINGER, DS
机构
[1] The Johns Hopkins Oncology Center, Baltimore, Maryland
关键词
SMALL CELL LUNG CANCER; CHEMOTHERAPY; PACLITAXEL; DOCETAXEL; CPT-11; TOPOTECAN; GEMCITABINE;
D O I
10.1016/S0169-5002(10)80018-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Recently there has been a number of new active drugs which have been identified for treating patients with SCLC. These drugs include paclitaxel, docetaxel, CPT-11, topotecan and gemcitabine. The range of response rates are as follows for each of the drugs given: (I) to previously untreated patients: paclitaxel (34-41%), topotecan (39%) and gemcitabine (30%), and (2) to previously treated patients: docetaxel (28%), CPT-11 (47%) and topotecan (35%). Further studies with these new drugs utilized in combination chemotherapeutic regimens are needed to define the role of these agents in the treatment of patients with SCLC.
引用
收藏
页码:S53 / S61
页数:9
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