REGIOSELECTIVE ENZYMATIC DEACETYLATION OF SUCROSE OCTAACETATE IN ORGANIC-SOLVENTS

被引：20
|
作者：
PALMER, DC [1 ]
TERRADAS, F [1 ]
机构：
[1] MCNEIL SPECIALTY PROD CO, ATHENS, GA 30608 USA
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 11期
关键词：
D O I：
10.1016/0040-4039(94)88316-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first examples of deacetylation of sucrose octaacetate using proteases and lipases in organic solvents are reported. The regiochemistry of the product sucrose hepta-, hexa- and pentaacetates was established by perdeuteroacetylation and H-1-NMR. Preparation of key intermediates in the commercial synthesis of the high intensity sweetener, sucralose was achieved.
引用
收藏
页码：1673 / 1676
页数：4
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