We report two cases of partial complex epilepsy associated with a lesion of the corpus callosum : a cavernoma in one case and a lesion of undertermined nature in the other. Similar cases have already been reported, notably with lipomas or agenesis of the corpus callosum, but they remain exceptional. Two mechanisms could explain such epilepsies: either the lesion extends to the cingulate gyrus whence the epileptic discharge may reach internal temporal structures (our case n-degrees 1), or a temporal focus becomes autonomic after interruption of inhibitory callosal fibres (our case n-degrees 2).