MAY THERE EXIST SPECIFIC MRI FINDINGS PREDICTIVE OF DEMENTIA IN MULTIPLE-SCLEROSIS PATIENTS

被引：0
|
作者：
PATTI, F
DISTEFANO, M
DEPASCALIS, D
CIANCIO, MR
DEBERNARDIS, E
NICOLETTI, F
REGGIO, A
机构：
[1] UNIV CATANIA,SCH MED,CTR MULTIPLE SCLEROSIS,INST NEUROSCI,CATANIA,ITALY
[2] UNIV CATANIA,SCH MED,INST PHARMACOL,I-95125 CATANIA,ITALY
[3] UNIV PERUGIA,DEPT EXPTL MED & BIOCHEM SCI,PHARMACOL SECT,I-06100 PERUGIA,ITALY
来源：
FUNCTIONAL NEUROLOGY | 1995年 / 10卷 / 02期
关键词：
COGNITIVE IMPAIRMENT; CONFLUENT PLAQUES; MRI; MULTIPLE SCLEROSIS;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Cognitive deficits are present in a substantial number of Multiple Sclerosis (MS) patients, particularly in those with the chronic-progressive type of the disorder. We assessed cognitive decline and its relationship with T2-weighted images on magnetic resonance imaging (MRI). We submitted a group of 26 patients with progressive MS to both MRI and a battery of neuropsychological tests. Cognitive impairment did not correlate with duration of illness or severity of neurological disability, but rather with the presence of extensive periventricular demyelination on MRI, evaluated as area of confluent lesions. These results suggest that cognitive deficits in MS represent a symptom of disease and not a parallel occurrence.
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页码：83 / 90
页数：8
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