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EXPRESSION OF VIMENTIN IN GASTRIC-CANCER - A POSSIBLE INDICATOR FOR PROGNOSIS
被引:21
|作者:
TAKEMURA, K
HIRAYAMA, R
HIROKAWA, K
INAGAKI, M
TSUJIMURA, K
ESAKI, Y
MISHIMA, Y
机构:
[1] TOKYO MED & DENT UNIV, DEPT SURG 2, TOKYO, JAPAN
[2] TOKYO METROPOLITAN GERIATR HOSP & INST GERONTOL, DEPT PATHOL, TOKYO, JAPAN
[3] TOKYO METROPOLITAN GERIATR HOSP & INST GERONTOL, DEPT NEUROPHYSIOL, TOKYO, JAPAN
关键词:
VIMENTIN;
GASTRIC CANCER;
INTERMEDIATE FILAMENT;
IMMUNOHISTOLOGY;
D O I:
10.1159/000163895
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
Expression of vimentin in gastric cancer was immunohistologically examined in 85 surgically resected specimens and evaluated in terms of various clinicopathological. features. Vimentin expression was more pronounced in gastric cancers of more advanced type and in those exhibiting a higher degree of infiltrative growth, lymph node involvement and vascular invasion. These results indicate that vimentin expression by gastric cancer might be related to the invasion and metastatic process of cancer cells and could be useful as a prognostic indicator for patients with gastric cancer.
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页码:149 / 154
页数:6
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