SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME BENZOPYRANONE IMINO DERIVATIVES OF GABA AND RELATED-COMPOUNDS

被引：0
|
作者：
ARNOLDI, A
MERLINI, L
QUADRI, ML
BONSIGNORI, A
MELLONI, P
VARASI, M
机构：
[1] UNIV MILAN,DIPARTIMENTO SCI MOLEC AGROALIMENTARI,CHIM SEZ,VIA CELORIA 2,I-20133 MILAN,ITALY
[2] FARMITALIA CARLO ERBA SPA,RES & DEV ERBAMONT GRP,I-20159 MILAN,ITALY
来源：
FARMACO | 1991年 / 46卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The synthesis of some 5-hydroxy-4-imino-2,3-dihydrobenzopyran derivatives of GABA and alkylamines is described. The products were tested for their GABA-receptor binding and anticonvulsant activity in mice. Some compounds showed anticonvulsant activity. No binding to GABA receptors was observed.
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页码：629 / 638
页数：10
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