ENHANCED URINARY-EXCRETION OF LEUKOTRIENE E4 IN PATIENTS WITH MEVALONATE KINASE-DEFICIENCY

被引：15
|
作者：
MAYATEPEK, E
HOFFMANN, GF
BREMER, HJ
机构：
[1] University Children's Hospital, Heidelberg
来源：
JOURNAL OF PEDIATRICS | 1993年 / 123卷 / 01期
关键词：
D O I：
10.1016/S0022-3476(05)81548-3
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
In patients with mevalonate kinase deficiency, urinary excretion of the leukotriene LTE4 was found to be elevated. A positive linear relationship between increased urinary excretion of mevalonate and LTE4 ( n = 5) suggests that increased cysteinyl leukotriene synthesis is involved in the pathomechanisms of this disease.
引用
收藏
页码：96 / 98
页数：3
相关论文
共 50 条
  • [31] Urinary leukotriene E4 in Henoch-Schonlein purpura
    Tsuji, Y
    Abe, Y
    Hisano, M
    Sakai, T
    CLINICAL AND EXPERIMENTAL ALLERGY, 2004, 34 (08): : 1259 - 1261
  • [32] Circadian characteristics of urinary leukotriene E4 in healthy subjects and nocturnal asthmatic patients
    Kurokawa, K
    Tanaka, H
    Tanaka, S
    Abe, S
    CHEST, 2001, 120 (06) : 1822 - 1828
  • [33] Nasal blockage and urinary leukotriene E4 concentration in patients with seasonal allergic rhinitis
    Higashi, N
    Taniguchi, M
    Mita, H
    Ishii, T
    Akiyama, K
    ALLERGY, 2003, 58 (06) : 476 - 480
  • [34] Urinary leukotriene E4 excretion during the first month of life and subsequent bronchopulmonary dysplasia in premature infants
    Sheikh, S
    Null, D
    Gentile, D
    Bimle, C
    Skoner, D
    McCoy, K
    Guthrie, R
    CHEST, 2001, 119 (06) : 1749 - 1754
  • [35] Clinical features of asthmatic patients with increased urinary leukotriene E4 excretion (hyperleukotrienuria): Involvement of chronic hyperplastic rhinosinusitis with nasal polyposis
    Higashi, N
    Taniguchi, M
    Mita, H
    Kawagishi, Y
    Ishii, T
    Higashi, A
    Osame, M
    Akiyama, K
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (02) : 277 - 283
  • [36] Urinary leukotriene E4 excretion is increased in type 1 diabetic patients -: A quantification by liquid chromatography-tandem mass spectrometry
    Hardy, G
    Boizel, R
    Bessard, J
    Cracowski, JL
    Bessard, G
    Halimi, S
    Stanke-Labesque, F
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2005, 78 (1-4) : 291 - 299
  • [37] Urinary leukotriene E4 (LTE4) levels in children.
    Westcolt, JY
    Bratton, DL
    Krawiec, ME
    Wenzel, SE
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) : A96 - A96
  • [38] The future of recurring restenosis prediction - Urinary cysteinyl leukotriene e4
    Maga, M.
    Wachsmann, A.
    Maga, P.
    EUROPEAN HEART JOURNAL, 2019, 40 : 2454 - 2454
  • [39] Strenuous exercise increases plasmatic and urinary leukotriene E4 in cyclists
    Caillaud, C
    Le Creff, C
    Legros, P
    Denjean, A
    CANADIAN JOURNAL OF APPLIED PHYSIOLOGY-REVUE CANADIENNE DE PHYSIOLOGIE APPLIQUEE, 2003, 28 (06): : 793 - 806
  • [40] URINARY LEUKOTRIENE E4 AFTER EXERCISE CHALLENGE IN CHILDREN WITH ASTHMA
    KIKAWA, Y
    MIYANOMAE, T
    INOUE, Y
    SAITO, M
    NAKAI, A
    SHIGEMATSU, Y
    HOSOI, S
    SUDO, M
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 89 (06) : 1111 - 1119
12345