RETINOPATHY OF PREMATURITY - PREVALENCE AND TREATMENT OVER A 20 YEAR PERIOD AT PENNSYLVANIA-HOSPITAL

被引：4

作者：

JOHNSON, LH

QUINN, GE

ABBASI, S

BOWEN, FW

机构：

[1] UNIV PENN, SCH MED, DEPT OPHTHALMOL, PHILADELPHIA, PA 19107 USA

[2] UNIV PENN, SCH MED, DEPT PEDIAT, PHILADELPHIA, PA 19107 USA

来源：

DOCUMENTA OPHTHALMOLOGICA | 1990年 / 74卷 / 03期

关键词：

perinatal care; pharmacologic; physiologic; retinopathy of prematurity; survival rates; vitamin E;

D O I：

10.1007/BF02482611

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

This paper presents the results of a 20 year survey of ROP among ≤ 2000 g BW infants cared for at Pennsylvania Hospital. It relates changes in perinatal care and nutrition, survival rates, and serial serum E levels with incidence and severity of ROP. It includes our protocol for monitoring E nutrition so as to optimize its effectiveness at physiologic serum levels for prophylaxis for ROP. Also presented are the promising results of our experience with vitamin E at pharmacologic serum levels as a treatment for severe ROP (defined as in the Cryo ROP Trial). These indicate the need for a multicenter trial to assess the effect of pharmacologic Vitamin E therapy as an alternative or supplement to therapy of severe ROP with laser or cryo surgery. © 1990 Kluwer Academic Publishers.

引用

页码：213 / 222

页数：10

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