CLINICAL PROFILE OF CHINESE PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS

被引:43
|
作者
LEE, SS
LI, CS
LI, PCK
机构
[1] Medical A Unit, Queen Elizabeth Hospital, Kowloon, Wylie Road
关键词
SYSTEMIC LUPUS ERYTHEMATOSUS; CHINESE; AUTOANTIBODIES;
D O I
10.1177/096120339300200207
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In the 9-year period between 1982 and 1991, 137 patients attending a medical clinic of Queen Elizabeth Hospital, Hong Kong, were diagnosed as having systemic lupus erythematosus according to the American Rheumatism Association's criteria for classification. The female-to-male ratio was 16 to 1. Commonly the onset age was between 20 and 40. Malar rash (70%), arthritis (70.8%) and nephropathy (69.3%) were the most common manifestations. Antinuclear factor was invariably positive, whereas anti-extractable nuclear antigen antibodies were positive in varying degrees - Sm 12.7%, nRNP 28.8%, Ro 60.2%, La 8.4%. There were 22 deaths during the follow-up period, two-thirds from active diseases. Gastro-intestinal bleeding and opportunistic infection were common complications.
引用
收藏
页码:105 / 109
页数:5
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