SYNTHESIS AND PER-FUNCTIONALIZATION OF HEPTAKIS(6-O-CARBOXYMETHYL-2,3-DI-O-METHYL)CYCLOMALTOHEPTAOSE

被引：13
|
作者：
AKERFELDT, KS [1 ]
DEGRADO, WF [1 ]
机构：
[1] DUPONT CO INC,EXPTL STN,WILMINGTON,DE 19880
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 26期
关键词：
D O I：
10.1016/S0040-4039(00)60708-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Tile synthesis and isolation of heptakis(6-O- carboxymethyl-2,3-di-O-methyl)cyclomalto-heptaose is described. The method provides a homogeneous product that carl be used as a scaffold for the covalent attachment of a defined number of peptides, lipids, or other compounds in preparing supramolecular assemblies. In this report we describe the addition of tryptophan methyl ester and a 7-residue peptide, H2N-WSLSLSL-CONH2, to the percarboxymethylated cyclodextrin carrier.
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页码：4489 / 4492
页数：4
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