Synthesis of a hexacyclopeptide on solid support using BOP reagent

被引：0
|
作者：
Han, ZJ [1 ]
Ding, ZK [1 ]
Zhang, QK [1 ]
机构：
[1] Beijing Inst Pharmacol & Toxicol, Beijing 100850, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 1995年 / 6卷 / 08期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The linear hexapeptide(His-Gly-Asp-Ser-Gly-Asp) was synthesized on solid support. FM group was used for alpha carboxyl protection group at Asp1. Peptide was cyclized by BOP reagent while still attached to the solid support. BOP procedure proceeded more rapidly aid gave purer product than DCC/HOBt method.
引用
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页码：667 / 668
页数：2
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