THE LIFESAVING EFFECT OF PHYSOSTIGMINE IN HEMORRHAGIC-SHOCK

被引：16
|
作者：
SAVIC, J
VARAGIC, VM
PROKIC, D
VUJNOV, S
PROSTRAN, M
ZUNIC, G
STANIMIROVIC, D
RASTOVACBOGDANOVIC, M
机构：
[1] Department of Pharmacology, Faculty of Medicine
来源：
RESUSCITATION | 1991年 / 21卷 / 01期
关键词：
PHYSOSTIGMINE; BLOOD PRESSURE; CENTRAL CONTROL OF BLOOD PRESSURE; HEMORRHAGIC SHOCK;
D O I：
10.1016/0300-9572(91)90078-D
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
The intravenous injection of physostigmine (70-mu-g kg-1) produces a life-saving effect in acute haemorrhagic shock in non-anaesthetized rabbits. This effect is most probably due to a transfer of tissue fluids into circulation. The crucial beneficial effect of physostigmine might be a decrease of the capillary hydrostatic pressure due to changes in pre- to postcapillary resistance ratio. Both lines of defence comprise a normalization of blood pressure and normalization of blood volume, thus saving the life of the animal.
引用
收藏
页码：57 / 60
页数：4
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