MELANOCYTE MUTATION IN HALO NEVUS AND MALIGNANT-MELANOMA

被引：11
|
作者：
BENNETT, C
COPEMAN, PWM
机构：
[1] WESTMINSTER MED SCH, DEPT CHEM PATHOL, PHYS BIOCHEM LAB, LONDON SW1, ENGLAND
[2] WESTMINSTER HOSP, DEPT DERMATOL, LONDON SW1, ENGLAND
来源：
BRITISH JOURNAL OF DERMATOLOGY | 1979年 / 100卷 / 04期
关键词：
D O I：
10.1111/j.1365-2133.1979.tb01643.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Halo nevus cells on frozen sections react with sera from patients with benign halo nevus or with malignant melanoma. Halo nevus cells also react with our specifically absorbed heterologous antihuman malignant melanoma antiserum (RAMMA). Since the cytoplasm of all the nevus cells within the halo nevus react with sera from patients with malignant melanoma, the entire population of melanocytic cells in the mole apparently underwent mutation, because non-pathological skin melanocytes do not react.
引用
收藏
页码：423 / 426
页数：4
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