ACUTE MYELOMONOCYTIC LEUKEMIA WITH BONE-MARROW EOSINOPHILIA AND INV(16)(P13Q22),T(1-16)(Q32-Q22)

被引：20
|
作者：
YIP, MY [1 ]
SHARMA, P [1 ]
WHITE, L [1 ]
机构：
[1] PRINCE WALES CHILDRENS HOSP, DEPT HAEMATOL ONCOL, SYDNEY, AUSTRALIA
来源：
CANCER GENETICS AND CYTOGENETICS | 1991年 / 51卷 / 02期
关键词：
D O I：
10.1016/0165-4608(91)90136-I
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A two-year-old girl presenting with de novo acute myelomonocytic leukemia with eosinophilia (French-American-British [FAB] classification, M4Eo) and inv(16)(p13q22), t(1;16)(q32;q22) involving the same chromosome 16 is described. This is the second report of a variant translocation of an inverted chromosome 16 with chromosome 1 at 1q32. However, the segment 1q32 --> 1qter has been exchanged for 16q22 --> qter and not 16p13 --> pter, as reported in the previous case. The additional break at 1q32 and the juxtaposition of 1q32 --> qter onto chromosome 16 could be relevant to the pathogenesis of the disease.
引用
收藏
页码：235 / 238
页数：4
相关论文
共 50 条
  • [1] ACUTE MYELOMONOCYTIC LEUKEMIA WITH MARROW EOSINOPHILIA (M4EO) AND INV(16)(P13Q22) IN A PATIENT WITH A HERITABLE FRAGILE SITE 16Q22
    ARTHUR, DC
    AASENG, SM
    BLOOMFIELD, CD
    CYTOGENETICS AND CELL GENETICS, 1985, 40 (1-4): : 572 - 572
  • [2] ACUTE MYELOMONOCYTIC LEUKEMIA WITH INV(16)(P13Q22) IN AN XY/XYY MALE
    OHYASHIKI, JH
    OHYASHIKI, K
    IWABUCHI, H
    LIN, KY
    TOYAMA, K
    CANCER GENETICS AND CYTOGENETICS, 1987, 29 (02) : 331 - 332
  • [3] A MORPHOLOGIC AND CYTOCHEMICAL STUDY OF ACUTE MYELOMONOCYTIC LEUKEMIA WITH ABNORMAL MARROW EOSINOPHILS ASSOCIATED WITH INV(16)(P13Q22)
    BITTER, MA
    LEBEAU, MM
    LARSON, RA
    ROSNER, MC
    GOLOMB, HM
    ROWLEY, JD
    VARDIMAN, JW
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1984, 81 (06) : 733 - 741
  • [4] HYPOPLASTIC ACUTE-LEUKEMIA ASSOCIATED WITH INV(16)(P13Q22)
    NAKAMURA, H
    MAEDA, T
    KOHNO, T
    SADAMORI, N
    ICHIMARU, M
    CANCER GENETICS AND CYTOGENETICS, 1991, 51 (01) : 63 - 66
  • [5] A case with a cytogenetically cryptic variant of the inv(16)(p13q22)/t(16;16)(p13;q22)
    Van Obbergh, Florence
    Michaux, Lucienne
    Maertens, Johan
    Schoemans, Helene
    Vandenberghe, Peter
    CANCER GENETICS, 2014, 207 (05) : 231 - 232
  • [6] Acute myelomonocytic leukemia with dysplastic bone marrow eosinophils showing t(5;17)(q13;q11) and a secondary chromosomal aberration, inv(16)(p13q22)
    Sakai, Rika
    Fujimaki, Katsumichi
    Yamazaki, Etsuko
    Sakamoto, Hiroshi
    Kanamori, Heiwa
    Miura, Ikuo
    Ishigatsubo, Yoshiaki
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2006, 84 (05) : 417 - 420
  • [7] Acute Myelomonocytic Leukemia with Dysplastic Bone Marrow Eosinophils Showing t(5;17)(q13;q11) and a Secondary Chromosomal Aberration, inv(16)(p13q22)
    Rika Sakai
    Katsumichi Fujimaki
    Etsuko Yamazaki
    Hiroshi Sakamoto
    Heiwa Kanamori
    Ikuo Miura
    Yoshiaki Ishigatsubo
    International Journal of Hematology, 2006, 84 : 417 - 420
  • [8] Clustering of genomic inv(16)(p13q22) breakpoints in acute nonlymphocytic leukemia
    vanderReijden, BA
    Wijmenga, C
    Liu, P
    Dauwerse, JG
    Giles, RH
    Changur, S
    vanOmmen, GJ
    Hagemeijer, A
    Breuning, M
    BLOOD, 1995, 86 (10) : 2968 - 2968
  • [9] The prognostic significance of 3′ CBFB deletions in inv(16)(p13q22)/t(16;16)(p13;q22)
    Huxley, E
    Griffiths, MJ
    Talley, P
    Whitworth, A
    Humphreys, M
    McKinley, M
    JOURNAL OF MEDICAL GENETICS, 2005, 42 : S81 - S81
  • [10] ACUTE PROMYELOCYTIC LEUKEMIA WITH T(15;17) (Q22;Q21) DEVELOPING INV(16)(P13Q22) SECONDARY AML
    Akiki, J.
    Jeffries, S.
    Craddock, Ch.
    Griffiths, M.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 543 - 543
12345