N-EPSILON-CARBOXYMETHYLLYSINE FORMATION BY DIRECT ADDITION OF GLYOXAL TO LYSINE DURING THE MAILLARD REACTION

被引：23
|
作者：
ALABED, Y
BUCALA, R
机构：
[1] The Picower Institute For Medical Research, Manhasset, NY 11030
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 18期
关键词：
D O I：
10.1016/0960-894X(95)00375-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Glyoxal, a retro-aldol cleavage product of the Maillard reaction, is a likely intermediate for the formation of N-epsilon-carboxymethyllysine upon incubation with lysine under physiological conditions.
引用
收藏
页码：2161 / 2162
页数：2
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