LOCALIZATION OF THE GENE FOR MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A TO A 480-KB REGION IN CHROMOSOME BAND 10Q11.2

被引：97
|
作者：
MOLE, SE [1 ]
MULLIGAN, LM [1 ]
HEALEY, CS [1 ]
PONDER, BAJ [1 ]
TUNNACLIFFE, A [1 ]
机构：
[1] UNIV CAMBRIDGE,DEPT PATHOL,CRC HUMAN CANC GENET RES GRP,TENNIS COURT RD,CAMBRIDGE CB2 1QP,ENGLAND
来源：
HUMAN MOLECULAR GENETICS | 1993年 / 2卷 / 03期
关键词：
D O I：
10.1093/hmg/2.3.247
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A YAC contig has been constructed spanning 1.1 Mb of human chromosome band 10q11.2 which encompasses three markers (D10S141, RET, D10S94) closely linked to the gene for MEN 2A. This physical linkage group is ordered cen-D10S141-RET-D10S94-qter, and must include MEN2A, which lies in a 480 kb region between flanking markers D10S141 and D10S94.
引用
收藏
页码：247 / 252
页数：6
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