PRALIDOXIME IN THE TREATMENT OF CARBAMATE INTOXICATION

被引：15
|
作者：
KURTZ, PH
机构：
来源：
AMERICAN JOURNAL OF EMERGENCY MEDICINE | 1990年 / 8卷 / 01期
关键词：
2-PAM; aldicarb; carbamate poisoning; carbaryl; cholinesterase reactivators; obidoxime; Oximes; P2S; pralidoxime;
D O I：
10.1016/0735-6757(90)90299-F
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
The use of oxime reactivators of inhibited cholinesterase enzymes in poisoning by carbamate compounds has received mixed reviews in the medical literature. Data are limited and inconsistent on the possible role oxime reactivators might have in carbamate intoxication. Based on existing experience, atropine remains the treatment of choice and pralidoxime (2-PAM) is not recommended except in cases where atropine has first been proven inadequate, in serious mixed poisonings with both carbamate and organophosphorus compounds, or in serious poisonings by unidentified cholinesterase inhibitors. © 1990.
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页码：68 / 70
页数：3
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