FACIAL-NERVE LESIONS LEAD TO INCREASED IMMUNOSTAINING OF THE ASTROCYTIC GAP JUNCTION PROTEIN (CONNEXIN 43) IN THE CORRESPONDING FACIAL NUCLEUS OF RATS

被引：51

作者：

ROHLMANN, A ^{[1
]}

LASKAWI, R ^{[1
]}

HOFER, A ^{[1
]}

DOBO, E ^{[1
]}

DERMIETZEL, R ^{[1
]}

WOLFF, JR ^{[1
]}

机构：

[1] UNIV REGENSBURG,DEPT ANAT,W-8400 REGENSBURG,GERMANY

来源：

NEUROSCIENCE LETTERS | 1993年 / 154卷 / 1-2期

关键词：

ASTROCYTE; CONNEXIN-43; COUPLING; FACIAL NUCLEUS; GAP JUNCTION; NEURONAL-GLIAL INTERACTION;

D O I：

10.1016/0304-3940(93)90208-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

After peripheral transection of the facial nerve, immunostaining of astrocytic gap junction protein changed in the corresponding brainstem nucleus of the rat. Enhanced connexin-43 immunoreactivity was restricted to the ipsilateral facial nucleus and to astrocytes surrounding lesioned motoneurons. This reaction is focally distinct, and marks only a part of the astrocytic network indicating a local plasticity of intercellular coupling. These results suggest that astrocytes work as sensors of signals which either depend on the integrity of neighboring neurons or inform about neuronal disorders.

引用

页码：206 / 208

页数：3

共 27 条

[21] UP-REGULATION OF B-50/GAP-43 IN SCHWANN-CELLS AT DENERVATED MOTOR END-PLATES AND IN MOTONEURONS AFTER RAT FACIAL-NERVE CRUSH
ULENKATE, HJLM
VERHAAGEN, J
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GISPEN, WH
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RESTORATIVE NEUROLOGY AND NEUROSCIENCE, 1993, 6 (01) : 35 - 47
[22] ALLOGENEIC BONE MARROW MESENCHYMAL STEM CELLS OVER-EXPRESSING GAP JUNCTION PROTEIN CONNEXIN 43 REDUCE VENTRICULAR ARRHYTHMIAS FOLLOWING MYOCARDIAL INFARCTION IN RATS
Xi, Hui
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HEART, 2011, 97
[23] Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4, gap junction protein connexin-43 and synaptophysin after stroke in rats
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[24] Growth associated protein-43 (GAP-43) and L-histidine decarboxylase (HDC) expression levels in tuberomammillary (TM) nucleus of rats with unilateral striatal lesions
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Panula, P
INFLAMMATION RESEARCH, 2002, 51 : S42 - S43
[25] Growth associated protein-43 (GAP-43) and L-histidine decarboxylase (HDC) expression levels in tuberomammillary (TM) nucleus of rats with unilateral striatal lesions
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Inflammation Research, 2002, 51 (Suppl 1) : 42 - 43
[26] Endothelial progenitor cell (EPC) transplantation improves myocardial infarction via up-regulation of vascular endothelial growth factor and gap junction protein connexin 43 in rats
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Yang, Guanghui
Sheng, Guotai
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INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 11 (03): : 1805 - 1814
[27] INCREASE IN MESSENGER-RIBONUCLEIC-ACID ENCODING THE MYOMETRIAL GAP JUNCTION PROTEIN, CONNEXIN-43, REQUIRES PROTEIN-SYNTHESIS AND IS ASSOCIATED WITH INCREASED EXPRESSION OF THE ACTIVATOR PROTEIN-1, C-FOS
PIERSANTI, M
LYE, SJ
ENDOCRINOLOGY, 1995, 136 (08) : 3571 - 3578

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