FACIAL-NERVE LESIONS LEAD TO INCREASED IMMUNOSTAINING OF THE ASTROCYTIC GAP JUNCTION PROTEIN (CONNEXIN 43) IN THE CORRESPONDING FACIAL NUCLEUS OF RATS

被引：51

作者：

ROHLMANN, A ^{[1
]}

LASKAWI, R ^{[1
]}

HOFER, A ^{[1
]}

DOBO, E ^{[1
]}

DERMIETZEL, R ^{[1
]}

WOLFF, JR ^{[1
]}

机构：

[1] UNIV REGENSBURG,DEPT ANAT,W-8400 REGENSBURG,GERMANY

来源：

NEUROSCIENCE LETTERS | 1993年 / 154卷 / 1-2期

关键词：

ASTROCYTE; CONNEXIN-43; COUPLING; FACIAL NUCLEUS; GAP JUNCTION; NEURONAL-GLIAL INTERACTION;

D O I：

10.1016/0304-3940(93)90208-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

After peripheral transection of the facial nerve, immunostaining of astrocytic gap junction protein changed in the corresponding brainstem nucleus of the rat. Enhanced connexin-43 immunoreactivity was restricted to the ipsilateral facial nucleus and to astrocytes surrounding lesioned motoneurons. This reaction is focally distinct, and marks only a part of the astrocytic network indicating a local plasticity of intercellular coupling. These results suggest that astrocytes work as sensors of signals which either depend on the integrity of neighboring neurons or inform about neuronal disorders.

引用

页码：206 / 208

页数：3

共 27 条

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