GRANULOMAS ASSOCIATED WITH TETANUS TOXOID IMMUNIZATION

被引:23
|
作者
COMINOS, D
STRUTTON, G
BUSMANIS, I
机构
[1] ROYAL MELBOURNE HOSP,DEPT ANAT PATHOL,PARKVILLE,VIC 3050,AUSTRALIA
[2] QUEENSLAND MED LAB,BRISBANE,AUSTRALIA
关键词
TETANUS TOXOID; ALUMINUM; GRANULOMA;
D O I
10.1097/00000372-199304000-00003
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Two patients developed localized nodular reactions at the site of prior tetanus toxoid injections. Histology of the lesions showed granuloma formation with central granular debris surrounded by a histiocytic mantle. Peripheral to this was a dense lymphoid infiltrate with eosinophils. Examination with energy dispersive x-ray microanalysis confirmed the presence of aluminium and phosphorus in the granular debris but not in the surrounding infiltrate.
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页码:114 / 117
页数:4
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