DIASTEREOSELECTIVE CONJUGATE ADDITION OF AMMONIA IN THE SYNTHESIS OF CHIRAL PYRROLIDINES

被引：21

作者：

ROBINA, I ^{[1
]}

GEARING, RP ^{[1
]}

BUCHANAN, JG ^{[1
]}

WIGHTMAN, RH ^{[1
]}

机构：

[1] HERIOT WATT UNIV,DEPT CHEM,EDINBURGH EH14 4AS,MIDLOTHIAN,SCOTLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 09期

关键词：

D O I：

10.1039/p19900002622

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

threo-Selectivity in the conjugate addition of ammonia to 4,5-isopropylidenedioxypent-2-enoic esters has been exploited in a new synthesis of homochiral pyrrolidines; the origin of the diastereoselectivity is discussed.

引用

页码：2622 / 2624

页数：3

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