PROINSULIN TRAFFICKING AND PROCESSING IN THE PANCREATIC B-CELL

被引：25
|
作者：
HALBAN, PA
机构：
[1] Laboratoires de Recherche Louis Jeantet, Centre Médical Universitaire, University of Geneva Medical School, CH-1211 Geneva 4, 1, rue Michel-Servet
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1990年 / 1卷 / 05期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/1043-2760(90)90007-P
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Insulin is synthesized as a precursor, preproinsulin, in the rough endoplasmic reticulum of the pancreatic B cell. The combination of precursor processing and the movement of products in vesicles from one subcellular compartment to the next results in insulin becoming stored in secretory granules ready for release in response to a secretagogue. © 1990.
引用
收藏
页码：261 / 265
页数：5
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