AN AQUEOUS EXTRACT OF GUARANA (PAULLINIA-CUPANA) DECREASES PLATELET THROMBOXANE SYNTHESIS

被引:0
|
作者
BYDLOWSKI, SP [1 ]
DAMICO, EA [1 ]
CHAMONE, DAF [1 ]
机构
[1] UNIV SAO PAULO,FAC MED,BR-05403 SAO PAULO,BRAZIL
关键词
GUARANA; PLATELET AGGREGATION; THROMBOXANE SYNTHESIS;
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The effects of an aqueous extract of guarana (Paullinia cupana) on rabbit platelet aggregation and thromboxane synthesis were examined. The guarana extract (100 mg/ml) and fractions separated by TLC (origin and xanthines) decreased platelet aggregation (37, 27 and 31% of control values, respectively) and platelet thromboxane formation from [C-14]-arachidonic acid (78, 70 and 50% of control values, respectively). The decreased thromboxane synthesis could be responsible, at least in part, for the anti-aggregatory action of guarana.
引用
收藏
页码:421 / 424
页数:4
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