AN AQUEOUS EXTRACT OF GUARANA (PAULLINIA-CUPANA) DECREASES PLATELET THROMBOXANE SYNTHESIS

被引：0
|
作者：
BYDLOWSKI, SP [1 ]
DAMICO, EA [1 ]
CHAMONE, DAF [1 ]
机构：
[1] UNIV SAO PAULO,FAC MED,BR-05403 SAO PAULO,BRAZIL
来源：
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH | 1991年 / 24卷 / 04期
关键词：
GUARANA; PLATELET AGGREGATION; THROMBOXANE SYNTHESIS;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The effects of an aqueous extract of guarana (Paullinia cupana) on rabbit platelet aggregation and thromboxane synthesis were examined. The guarana extract (100 mg/ml) and fractions separated by TLC (origin and xanthines) decreased platelet aggregation (37, 27 and 31% of control values, respectively) and platelet thromboxane formation from [C-14]-arachidonic acid (78, 70 and 50% of control values, respectively). The decreased thromboxane synthesis could be responsible, at least in part, for the anti-aggregatory action of guarana.
引用
收藏
页码：421 / 424
页数：4
相关论文
共 37 条
  • [1] GUARANA (PAULLINIA-CUPANA KNUTZ)
    ROMMELSPACHER, H
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 1995, 120 (11) : 384 - 384
  • [2] A NOVEL PROPERTY OF AN AQUEOUS GUARANA EXTRACT (PAULLINIA-CUPANA) - INHIBITION OF PLATELET-AGGREGATION INVITRO AND INVIVO
    BYDLOWSKI, SP
    YUNKER, RL
    SUBBIAH, MTR
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 1988, 21 (03) : 535 - 538
  • [3] GUARANA (PAULLINIA-CUPANA) AS A COMMERCIAL CROP IN BRAZILIAN AMAZONIA
    ERICKSON, HT
    CORREA, MPF
    ESCOBAR, JR
    ECONOMIC BOTANY, 1984, 38 (03) : 273 - 286
  • [4] NO BROWN SUGAR, JUST GUARANA (PAULLINIA-CUPANA KUNTH)
    RABL, W
    SIGRIST, T
    KRIMINALISTIK, 1993, 47 (04): : 271 - 272
  • [5] GUARANA (PAULLINIA-CUPANA) INHIBITS AGGREGATION IN WHOLE-BLOOD
    CHAMONE, DAF
    IVANYSILVA, M
    CASSARO, C
    BELLOTTI, G
    MASSUMOTO, C
    HOSHIKAWAFUJIMURA, AY
    THROMBOSIS AND HAEMOSTASIS, 1987, 58 (01) : 474 - 474
  • [6] GENOTOXIC AND MUTAGENIC EFFECTS OF GUARANA (PAULLINIA-CUPANA) IN PROKARYOTIC ORGANISMS
    DAFONSECA, CAS
    LEAL, J
    COSTA, SS
    LEITAO, AC
    MUTATION RESEARCH, 1994, 321 (03): : 165 - 173
  • [7] GUARANA (PAULLINIA-CUPANA) REWARDS SEED DISPERSERS WITHOUT INTOXICATING THEM BY CAFFEINE
    BAUMANN, TW
    SCHULTHESS, BH
    HANNI, K
    PHYTOCHEMISTRY, 1995, 39 (05) : 1063 - &
  • [8] EFFECTIVE FEMALE FLOWER VARIATION ESTIMATE OF GUARANA TREE PAULLINIA-CUPANA VAR SORBILIS
    ESCOBAR, JR
    PESQUISA AGROPECUARIA BRASILEIRA, 1985, 20 (12) : 1365 - 1371
  • [9] ANALYZING GUARANA (PAULLINIA-CUPANA VAR SORBILIS) .1. HPLC DETERMINATION OF CAFFEINE, THEOBROMINE AND THEOPHYLLINE IN GUARANA SEEDS
    MARX, F
    PFEILSTICKER, K
    MAIA, JGS
    DEUTSCHE LEBENSMITTEL-RUNDSCHAU, 1985, 81 (12) : 390 - 392
  • [10] HPLC DETERMINATION OF CAFFEINE AND THEOPHYLLINE IN PAULLINIA-CUPANA KUNTH (GUARANA) AND COLA SPP SAMPLES
    BELLIARDO, F
    MARTELLI, A
    VALLE, MG
    ZEITSCHRIFT FUR LEBENSMITTEL-UNTERSUCHUNG UND-FORSCHUNG, 1985, 180 (05): : 398 - 401
1234