EXPRESSION OF THE HUMAN AMYLOID PRECURSOR PROTEIN GENE IN THE CNS OF TRANSGENIC MICE

被引：0
|
作者：
TRAPP, BD [1 ]
UNTERBECK, A [1 ]
BAYNEY, R [1 ]
SCANGOS, G [1 ]
WIRAK, D [1 ]
机构：
[1] JOHNS HOPKINS UNIV,BALTIMORE,MD 21218
来源：
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY | 1989年 / 48卷 / 03期
关键词：
D O I：
10.1097/00005072-198905000-00242
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：379 / 379
页数：1
相关论文
共 50 条
  • [41] Overexpression of FYN kinase exacerbates cellular and behavioral deficits in human amyloid precursor protein transgenic mice
    Chin, J
    Palop, JJ
    Puoliväli, J
    Massaro, C
    Yu, GQ
    Masliah, E
    Mucke, L
    NEUROBIOLOGY OF AGING, 2004, 25 : S18 - S18
  • [42] Changes in Amyloid-β and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein
    Maia, Luis F.
    Kaeser, Stephan A.
    Reichwald, Julia
    Hruscha, Michael
    Martus, Peter
    Staufenbiel, Matthias
    Jucker, Mathias
    SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (194)
  • [43] Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice
    Bondolfi, L
    Calhoun, M
    Ermini, F
    Kuhn, HG
    Wiederhold, KH
    Walker, L
    Staufenbiel, M
    Jucker, M
    JOURNAL OF NEUROSCIENCE, 2002, 22 (02): : 515 - 522
  • [44] Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter constructAppropriate cell-type expression, but not regulation in brain
    Kristal L. Wright
    David G. Morgan
    Xin Yu
    James R. Goss
    J. Michael Salbaum
    Karen Duff
    Marcia N. Gordon
    Journal of Molecular Neuroscience, 1999, 13 : 111 - 120
  • [45] The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human β-amyloid precursor protein transgenic mice
    Lee, JY
    Friedman, JE
    Angel, I
    Kozak, A
    Koh, JY
    NEUROBIOLOGY OF AGING, 2004, 25 (10) : 1315 - 1321
  • [46] Genetic cathepsin B deficiency reduces β-amyloid in transgenic mice expressing human wild-type amyloid precursor protein
    Hook, Vivian Y. H.
    Kindy, Mark
    Reinheckel, Thomas
    Peters, Christoph
    Hook, Gregory
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 386 (02) : 284 - 288
  • [47] Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
    Chapman, PF
    White, GL
    Jones, MW
    Cooper-Blacketer, D
    Marshall, VJ
    Irizarry, M
    Younkin, L
    Good, MA
    Bliss, TVP
    Hyman, BT
    Younkin, SG
    Hsiao, KK
    NATURE NEUROSCIENCE, 1999, 2 (03) : 271 - 276
  • [48] β-amyloid deposits in transgenic mice expressing human β-amyloid precursor protein have the same characteristics as those in Alzheimer's disease
    Terai, K
    Iwai, A
    Kawabata, S
    Tasaki, Y
    Watanabe, T
    Miyata, K
    Yamaguchi, T
    NEUROSCIENCE, 2001, 104 (02) : 299 - 310
  • [49] Aβ-dependent alteration in cerebrovascular autoregulation in transgenic mice overexpressing the Amyloid precursor protein
    Niwa, K
    Ashe, KH
    Carlson, G
    Iadecola, C
    STROKE, 2000, 31 (01) : 287 - 287
  • [50] Proteome profiling of Amyloid precursor protein E693Δtransgenic mice
    Takano, Masaoki
    Maekura, Kouji
    Otani, Mieko
    Sano, Keiji
    Hirota, Tooru
    Kadoyama, Keiichi
    Matsuyama, Shogo
    Tomiyama, Takami
    Mori, Hiroshi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115 : 201P - 201P
12345