METABOLIC APPROACH FOR REGULATION OF IL-1-BETA IN-VIVO

被引：0
|
作者：
YANG, TB
ZHU, XH
SHEN, BF
XU, WG
机构：
来源：
SCIENCE IN CHINA SERIES B-CHEMISTRY LIFE SCIENCES & EARTH SCIENCES | 1995年 / 38卷 / 03期
关键词：
INTERLEUKIN; 1-BETA; AUTOANTIBODY; METABOLISM REGULATION;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
IL-1 beta, the autoantibodies to IL-1 beta and IL-1 beta-containing immune complex in pleural effusion and cerebrospinal fluid were detected using anti-recombinant human IL-1 beta monoclonal antibody. The results indicate that IL-1 beta is detectable in some cases, and the amounts decrease gradually with the chemotherapy following the autoantibodies and the specific detectable immune complex. These autoantibodies may have a feedback effect, inhibiting the IL-1 beta activity, and forming the immune complex to speed the clearance of activated IL-1 beta.
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页码：345 / 351
页数：7
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