In depressive patients with different degrees of severity of the disorder hemispheric differences of the occipital and central EP peak amplitude and latency were estimated under the conditions of presentation of a neutral light stimulus, structural stimulus, and mental reproducing the structural stimulus during presentation of the neutral one. Affective responses to the stimuli were also taken into account. In non-psychotic depression hemispheric asymmetry was observed in all responses studied being correlated with the dominant affect. In anxiety most of the EP components were higher in the right hemisphere; in sad affect they were higher in the left hemisphere. In psychotic depression, irrespective of the dominant affect, EP characteristics were higher in the right hemisphere.