CURRENT ISSUES IN EVALUATING THE EFFICACY OF ORAL POLIOVIRUS VACCINE AND INACTIVATED POLIOVIRUS VACCINE IMMUNIZATION

被引:13
|
作者
PLOTKIN, SA
机构
[1] Pasteur Mérieux, Marnes-La-Coquette
关键词
ORAL POLIOVIRUS VACCINE; INACTIVATED POLIOVIRUS VACCINE;
D O I
10.1097/00006454-199112000-00032
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Although epidemic poliomyelitis in the United States has been eliminated, there are a number of current issues that concern the use of oral attenuated poliovirus vaccine in comparison with the new enhanced-potency inactivated vaccine. Although wild-type poliovirus is almost eradicated in developed nations, vaccine-induced polio exists, at a low but persistent rate. This article reviews the current issues and suggests a return to the the Institute of Medicine's 1988 recommendations concerning combined immunization with inactivated poliovirus vaccine and oral poliovirus vaccine.
引用
收藏
页码:979 / 981
页数:3
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