PITUITARY-ADRENAL AXIS RESPONSE TO ARGININE VASOPRESSIN IN PATIENTS WITH MAJOR DEPRESSION

被引：5
|
作者：
CARROLL, BT
MELLER, WH
KATHOL, RG
GEHRIS, TL
CARTER, JL
SAMUELSON, SD
PITTS, AF
机构：
[1] UNIV IOWA,COLL MED,DEPT PSYCHIAT,500 NEWTON RD,IOWA CITY,IA 52242
[2] MED COLL PENN,OAKDALE,PA
[3] UNIV TEXAS,COLL MED,SAN ANTONIO,TX 78285
[4] UNIV MINNESOTA,COLL MED,MINNEAPOLIS,MN 55455
[5] OHIO STATE UNIV,COLL MED,COLUMBUS,OH 43210
[6] UNIV IOWA,COLL MED,MED PSYCHIAT WARD,IOWA CITY,IA 52242
来源：
PSYCHIATRY RESEARCH | 1993年 / 46卷 / 02期
关键词：
AFFECTIVE DISORDER; ADRENOCORTICOTROPIC HORMONE; CORTISOL;
D O I：
10.1016/0165-1781(93)90014-8
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Arginine vasopressin (AVP) was administered to 21 patients with major depression and 20 normal control subjects. Thirty-two subjects also underwent an overnight dexamethasone suppression test. The patient group did not differ significantly from the control group in adrenocorticotropic hormone (ACTH) or cortisol response. Dexamethasone suppression status did not affect ACTH or cortisol response. This study supports the hypothesis that unlike the response to corticotropin releasing hormone, the ACTH response to AVP is not attenuated in depression.
引用
收藏
页码：119 / 126
页数：8
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