NATURAL DNA ABZYMES FROM SERA OF PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：0
|
作者：
GOLOLOBOV, GV [1 ]
YADAV, RP [1 ]
BOGOMOLOVA, AE [1 ]
BELOSTOTSKAYA, KM [1 ]
STHUROV, DV [1 ]
GABIBOV, AG [1 ]
机构：
[1] RUSSIAN ACAD SCI,ENGELHARDT INST MOLEC BIOL,MOSCOW,RUSSIA
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1993年 / 32卷 / 01期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Catalytic antibodies, possessing the endonuclease activity were purified from the sera of patients with Sle. The optimized method of their purification is proposed. Investigations on catalytic properties of antibodies including specificity to low molecular weight substrate. kinetic parameters of the reaction and metal-ion dependency have been carried out.
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页码：81 / 84
页数：4
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