Onset of Type 1 Diabetes Mellitus During Pegylated-interferon Alfa and Ribavirin Therapy for Chronic Hepatitis C Virus Infection

被引：1

作者：

Ranganathan, Raghini ^{[1
]}

Janarthanan, Krishnaveni ^{[1
]}

Rajasekaran, Senthilkumar ^{[1
]}

机构：

[1] PSG Inst Med Sci & Res, Dept Gastroenterol, Coimbatore 641004, Tamil Nadu, India

来源：

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY | 2012年 / 2卷 / 01期

关键词：

Diabetes mellitus; hepatitis C virus; interferon;

D O I：

10.1016/S0973-6883(12)60089-9

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A 16-year-old female was treated with pegylated-interferon (PEG-IFN) alfa (alpha)-2b and ribavirin combination therapy for chronic hepatitis C virus (HCV) infection. She attained rapid virological response. She presented with diabetic ketoacidosis after 41 weeks of therapy. Anti-glutamic acid decarboxylase antibodies and islet cell antibodies were negative. Her fasting serum C-peptide level was <0.1ng/mL, and the treatment course was completed. This case underlines the importance of periodic plasma glucose monitoring in patients during and after PEG-IFN and ribavirin therapy.

引用

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页码：86 / 87

页数：2

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