Onset of Type 1 Diabetes Mellitus During Pegylated-interferon Alfa and Ribavirin Therapy for Chronic Hepatitis C Virus Infection

被引：1
|
作者：
Ranganathan, Raghini [1 ]
Janarthanan, Krishnaveni [1 ]
Rajasekaran, Senthilkumar [1 ]
机构：
[1] PSG Inst Med Sci & Res, Dept Gastroenterol, Coimbatore 641004, Tamil Nadu, India
来源：
JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY | 2012年 / 2卷 / 01期
关键词：
Diabetes mellitus; hepatitis C virus; interferon;
D O I：
10.1016/S0973-6883(12)60089-9
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
A 16-year-old female was treated with pegylated-interferon (PEG-IFN) alfa (alpha)-2b and ribavirin combination therapy for chronic hepatitis C virus (HCV) infection. She attained rapid virological response. She presented with diabetic ketoacidosis after 41 weeks of therapy. Anti-glutamic acid decarboxylase antibodies and islet cell antibodies were negative. Her fasting serum C-peptide level was <0.1ng/mL, and the treatment course was completed. This case underlines the importance of periodic plasma glucose monitoring in patients during and after PEG-IFN and ribavirin therapy.
引用
收藏
页码：86 / 87
页数：2
相关论文
共 50 条
  • [1] Treatment response of chronic hepatitis C virus infection with pegylated-interferon and ribavirin
    Humphris, J. L.
    Ngu, M. C.
    Lee, A. U.
    [J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2006, 21 : A331 - A331
  • [2] Pegylated interferon with ribavirin therapy for chronic infection with the hepatitis C virus
    Foster, GR
    [J]. EXPERT OPINION ON PHARMACOTHERAPY, 2003, 4 (05) : 685 - 691
  • [3] Pegylated interferon and ribavirin therapy for chronic hepatitis C virus genotype 4 infection
    Legrand-Abravanel, F
    Nicot, F
    Boulestin, A
    Sandres-Sauné, K
    Vinel, JP
    Alric, L
    Izopet, J
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2005, 77 (01) : 66 - 69
  • [4] Pegylated interferon alfa and ribavirin for children with chronic hepatitis C
    Irit Rosen
    Michal Kori
    Orly Eshach Adiv
    Baruch Yerushalmi
    Nataly Zion
    Ron Shaoul
    [J]. World Journal of Gastroenterology, 2013, (07) : 1098 - 1103
  • [5] Pegylated interferon alfa and ribavirin for children with chronic hepatitis C
    Rosen, Irit
    Kori, Michal
    Adiv, Orly Eshach
    Yerushalmi, Baruch
    Zion, Nataly
    Shaoul, Ron
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 19 (07) : 1098 - 1103
  • [6] High incidence of type 1 diabetes mellitus during or shortly after treatment with pegylated interferon α for chronic hepatitis C virus infection
    Schreuder, Tim C. M. A.
    Gelderblom, Huub C.
    Weegink, Christine J.
    Hamann, Dorte
    Reesink, Henk W.
    DeVries, J. Hans
    Hoekstra, Joost B. L.
    Jansen, Peter L. M.
    [J]. LIVER INTERNATIONAL, 2008, 28 (01) : 39 - 46
  • [7] Unmasking of myasthenia gravis during pegylated Alfa 2 a interferon and ribavirin therapy for chronic hepatitis C
    Saleem, Ayesha
    [J]. JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, 2016, 66 (05) : 618 - 620
  • [8] Fatal Neutropenic Enterocolitis during Pegylated Interferon and Ribavirin Combination Therapy for Chronic Hepatitis C Virus Infection
    Kim, Ji Hun
    Jang, Jeong Won
    You, Chan Ran
    You, Si Young
    Jung, Mun Kyung
    Jung, Jin Hwan
    [J]. GUT AND LIVER, 2009, 3 (03) : 218 - 221
  • [9] TYPE II MIXED CRYOGLOBULINEMIA IN PATIENTS WITH HEPATITIS C VIRUS: TREATMENT WITH PEGYLATED-INTERFERON AND RIBAVIRIN
    Malaguarnera, Michele
    Scuderi, Laura
    Ardiri, Annalisa
    Malaguarnera, Giulia
    Bertino, Nicoletta
    Ruggeri, Irene Maria
    Greco, Carmela
    Ozyalcn, Erdogan
    Bertino, Emanuele
    Bertino, Gaetano
    [J]. ACTA MEDICA MEDITERRANEA, 2015, 31 (03): : 651 - 662
  • [10] Hepatitis C virus core protein substitutions affect the response to pegylated-interferon and ribavirin therapy
    Fatimah S. Alhamlan
    Mohammed N. Al-Ahdal
    Nisreen Z. Khalaf
    Ayman A. Abdo
    Faisal Sanai
    Hamad I. Al-Ashgar
    Ahmed A. Al-Qahtani
    [J]. BMC Genomics, 15 (Suppl 2)
12345