EFFECTS OF SYSTEMIC GLUCOSE INJECTION ON THE DEVELOPMENT OF AMYGDALA KINDLING IN RATS

被引：4

作者：

PRIEL, MR ^{[1
]}

BORTOLOTTO, ZA ^{[1
]}

CAVALHEIRO, EA ^{[1
]}

机构：

[1] ESCOLA PAULISTA MED SCH,NEUROL EXPTL LAB,R BOTUCATU,BR-04023 SAO PAULO,SP,BRAZIL

来源：

BEHAVIORAL AND NEURAL BIOLOGY | 1991年 / 56卷 / 03期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1016/0163-1047(91)90484-8

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The effects of systemic glucose administration on the development of electric amygdaloid kindling seizures were examined in Wistar rats. Daily intraperitoneal injections of glucose 100 mg/kg, 20 min prior to each amygdaloid stimulation did affect the rate of kindling development in comparison with the saline-injected group. The number of stimulations required to reach stage 5 was lower in animals treated with glucose. The facilitation of kindling development found in glucosetreated rats is related to a specific decrease in the number of stimulations needed to evolve from stage 2 to stage 3. These results indicate that systemic glucose administration facilitates amygdaloid kindling in rats. © 1991 Academic Press, Inc.

引用

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页码：314 / 318

页数：5

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