ELECTROPHYSIOLOGICAL CORRELATES OF INVOLVEMENT OF THE HYPOTHALAMIC AND THALAMIC-SUBCORTICAL HUMAN BRAIN STRUCTURES IN PATHOLOGICAL PROCESS

Comparative EEG studies (with the normative data control) were carried out in patients with different anatomic-topographical variants of craniopharyngiomae, effecting the hypothalamus (12 patients) and involving thalamo-subcortical structures in the pathological process (17 patients). Characteristics of EEG reorganization were found to be determined in the first instance by the stage of development of the focal process. Analysis of the regional characteristics and intercentral relations of the brain biopotentials revealed besides the common features, the differences in the effects of certain diencephalic structures on the spatial-temporal EEG organization. Hypothalamic areas exert mainly global influence on the EEG pattern formation. Thalamic structures influence genesis of the rhythmic activity forms and their intercentral relations more differentially and make more important contribution to the formation of the balanced (in norm) pattern of the brain electrical processes spatial-temporal organization.